human KDM5A shRNA silencing AAV

Cat. No: shAAV-212850

Availability: 6-8 weeks

Name: AAV-h-KDM5A-shRNA

This is an AAV expressing shRNA for silencing of Human KDM5A.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KDM5A
Gene Name: lysine demethylase 5A
Gene ID: 5927
Gene Synonyms: RBBP-2; RBBP2; RBP2
ORF Size: 4923 bp
RefSeq#: NM_001042603
Gene Description: KDM5A is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein.
UniGene ID: Hs.76272
HGNC ID: HGNC:9886