human SULT1A4 shRNA silencing AAV

Cat. No: shAAV-229819

Availability: 6-8 weeks

Name: AAV-h-SULT1A4-shRNA

This is an AAV expressing shRNA for silencing of Human SULT1A4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SULT1A4
Gene Name: sulfotransferase family 1A member 4
Gene ID: 445329
Gene Synonyms: HAST3; M-PST; ST1A3/ST1A4; ST1A4; TL-PST
ORF Size: 888 bp
RefSeq#: NM_001017390
Gene Description: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16, this gene and SULT1A3 arose from a segmental duplication. Read-through transcription exists between this gene and the upstream SLX1B (SLX1 structure-specific endonuclease subunit homolog B) gene that encodes a protein containing GIY-YIG domains.
UniGene ID: Hs.719110
HGNC ID: HGNC:30004