human FOSB shRNA silencing AAV

Cat. No: shAAV-209222

Availability: 4-5 weeks

Name: AAV-h-FOSB-shRNA

This is an AAV expressing shRNA for silencing of Human FOSB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FOSB
Gene Name: FosB proto-oncogene, AP-1 transcription factor subunit
Gene ID: 2354
Gene Synonyms: AP-1; G0S3; GOS3; GOSB
ORF Size: 1017 bp
RefSeq#: NM_006732
Gene Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.590958
HGNC ID: HGNC:3797