human ICAM2 shRNA silencing AAV

Cat. No: shAAV-211748

Availability: 4-5 weeks

Name: AAV-h-ICAM2-shRNA

This is an AAV expressing shRNA for silencing of Human ICAM2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ICAM2
Gene Name: intercellular adhesion molecule 2
Gene ID: 3384
Gene Synonyms: CD102
ORF Size: 828 bp
RefSeq#: NM_000873
Gene Description: ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.431460
HGNC ID: HGNC:5345