human CHN1 shRNA silencing AAV

Cat. No: shAAV-205176

Availability: 4-5 weeks

Name: AAV-h-CHN1-shRNA

This is an AAV expressing shRNA for silencing of Human CHN1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CHN1
Gene Name: chimerin 1
Gene ID: 1123
Gene Synonyms: ARHGAP2; CHN; DURS2; NC; RHOGAP2
ORF Size: 1380 bp
RefSeq#: NM_001822
Gene Description: CHN1 encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UniGene ID: Hs.654534
HGNC ID: HGNC:1943