human ARL1 shRNA silencing AAV

Cat. No: shAAV-201389

Availability: 4-5 weeks

Name: AAV-h-ARL1-shRNA

This is an AAV expressing shRNA for silencing of Human ARL1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ARL1
Gene Name: ADP ribosylation factor like GTPase 1
Gene ID: 400
Gene Synonyms: ARFL1
ORF Size: 546 bp
RefSeq#: NM_001177
Gene Description: ARL1 belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner.
UniGene ID: Hs.372616
HGNC ID: HGNC:692