human CTNS shRNA silencing AAV

Cat. No: shAAV-206254

Availability: 4-5 weeks

Name: AAV-h-CTNS-shRNA

This is an AAV expressing shRNA for silencing of Human CTNS.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CTNS
Gene Name: cystinosin, lysosomal cystine transporter
Gene ID: 1497
Gene Synonyms: CTNS-LSB; PQLC4
ORF Size: 1203 bp
RefSeq#: NM_004937
Gene Description: CTNS encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.187667
HGNC ID: HGNC:2518