mouse ESRP1 shRNA silencing AAV

Cat. No: shAAV-258718

Availability: 6-8 weeks

Name: AAV-m-ESRP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Esrp1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Esrp1
Gene Name: epithelial splicing regulatory protein 1
Gene ID: 207920
Gene Synonyms: 2210008M09Rik; A630065D16; BC031468; Rbm35a
ORF Size: 1335 bp
RefSeq#: NM_194055
Gene Description: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
UniGene ID: Mm.387719