human ADFP shRNA silencing AAV

Cat. No: shAAV-200445

Availability: 4-5 weeks

Name: AAV-h-ADFP-shRNA

This is an AAV expressing shRNA for silencing of Human PLIN2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PLIN2
Gene Name: perilipin 2
Gene ID: 123
Gene Synonyms: ADFP; ADRP
ORF Size: 1314 bp
RefSeq#: NM_001122
Gene Description: PLIN2 belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.3416
HGNC ID: HGNC:248