human PLK4 shRNA silencing AAV

Cat. No: shAAV-219215

Availability: 4-5 weeks

Name: AAV-h-PLK4-shRNA

This is an AAV expressing shRNA for silencing of Human PLK4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PLK4
Gene Name: polo like kinase 4
Gene ID: 10733
Gene Synonyms: MCCRP2; SAK; STK18
ORF Size: 2913 bp
RefSeq#: NM_014264
Gene Description: PLK4 encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
UniGene ID: Hs.172052
HGNC ID: HGNC:11397