human TNFSF4 shRNA silencing AAV

Cat. No: shAAV-226112

Availability: 4-5 weeks

Name: AAV-h-TNFSF4-shRNA

This is an AAV expressing shRNA for silencing of Human TNFSF4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TNFSF4
Gene Name: tumor necrosis factor superfamily member 4
Gene ID: 7292
Gene Synonyms: CD134L; CD252; GP34; OX-40L; OX4OL; TNLG2B; TXGP1
ORF Size: 402 bp
RefSeq#: NM_003326
Gene Description: TNFSF4 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
UniGene ID: Hs.181097
HGNC ID: HGNC:11934