human STAU2 shRNA silencing AAV

Cat. No: shAAV-224547

Availability: 4-5 weeks

Name: AAV-h-STAU2-shRNA

This is an AAV expressing shRNA for silencing of Human STAU2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: STAU2
Gene Name: staufen double-stranded RNA binding protein 2
Gene ID: 27067
Gene Synonyms: 39K2; 39K3
ORF Size: 1617 bp
RefSeq#: NM_014393
Gene Description: Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5% and 59.9% similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.561815
HGNC ID: HGNC:11371