human SLC39A8 shRNA silencing AAV

Cat. No: shAAV-223467

Availability: 4-5 weeks

Name: AAV-h-SLC39A8-shRNA

This is an AAV expressing shRNA for silencing of Human SLC39A8.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC39A8
Gene Name: solute carrier family 39 member 8
Gene ID: 64116
Gene Synonyms: BIGM103; CDG2N; LZT-Hs6; PP3105; ZIP8
ORF Size: 1383 bp
RefSeq#: NM_022154
Gene Description: SLC39A8 encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
UniGene ID: Hs.288034
HGNC ID: HGNC:20862