mouse PPM1A shRNA silencing AAV

Cat. No: shAAV-269161

Availability: 4-5 weeks

Name: AAV-m-PPM1A-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ppm1a.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ppm1a
Gene Name: protein phosphatase 1A, magnesium dependent, alpha isoform
Gene ID: 19042
Gene Synonyms: 2310003C21Rik; 2900017D14Rik; AI427932; AU017636; MMPa-2; MPPa-1
ORF Size: 1149 bp
RefSeq#: NM_008910
Gene Description: Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling.
UniGene ID: Mm.261045