mouse PELO shRNA silencing AAV

Cat. No: shAAV-268390

Availability: 4-5 weeks

Name: AAV-m-PELO-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pelo.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pelo
Gene Name: pelota homolog (Drosophila)
Gene ID: 105083
Gene Synonyms: AA409897; AI852218
ORF Size: 1158 bp
RefSeq#: NM_134058
Gene Description: Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential).
UniGene ID: Mm.476819