mouse CASP9 shRNA silencing AAV

Cat. No: shAAV-254566

Availability: 4-5 weeks

Name: AAV-m-CASP9-shRNA

This is an AAV expressing shRNA for silencing of Mouse Casp9.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Casp9
Gene Name: caspase 9
Gene ID: 12371
Gene Synonyms: AI115399; APAF-3; AW493809; CASP-9; Caspase-9; ICE-LAP6; Mch6
ORF Size: 1365 bp
RefSeq#: NM_015733
Gene Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP)|Function: Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UniGene ID: Mm.468800