human CXCR7 shRNA silencing AAV

Cat. No: shAAV-206347

Availability: 6-8 weeks

Name: AAV-h-CXCR7-shRNA

This is an AAV expressing shRNA for silencing of Human ACKR3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ACKR3
Gene Name: atypical chemokine receptor 3
Gene ID: 57007
Gene Synonyms: CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1
ORF Size: 1089 bp
RefSeq#: NM_020311
Gene Description: CXCR7 encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
UniGene ID: Hs.471751
HGNC ID: HGNC:23692