mouse PTPN11 shRNA silencing AAV

Cat. No: shAAV-269792

Availability: Immediate

Name: AAV-m-PTPN11-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ptpn11.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ptpn11
Gene Name: protein tyrosine phosphatase, non-receptor type 11
Gene ID: 19247
Gene Synonyms: 2700084A17Rik; AW536184; PTP1D; PTP2C; SAP-2; SH-PTP2; SH-PTP3; SHP-2; Shp2; Syp
ORF Size: 1782 bp
RefSeq#: NM_011202
Gene Description: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
UniGene ID: Mm.474046