human CNOT7 shRNA silencing AAV

Cat. No: shAAV-205614

Availability: 4-5 weeks

Name: AAV-h-CNOT7-shRNA

This is an AAV expressing shRNA for silencing of Human CNOT7.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CNOT7
Gene Name: CCR4-NOT transcription complex subunit 7
Gene ID: 29883
Gene Synonyms: CAF-1; CAF1; Caf1a; hCAF-1
ORF Size: 741 bp
RefSeq#: NM_013354
Gene Description: CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
UniGene ID: Hs.598387
HGNC ID: HGNC:14101