human CDT1 shRNA silencing AAV

Cat. No: shAAV-204903

Availability: 6-8 weeks

Name: AAV-h-CDT1-shRNA

This is an AAV expressing shRNA for silencing of Human CDT1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CDT1
Gene Name: chromatin licensing and DNA replication factor 1
Gene ID: 81620
Gene Synonyms: DUP; RIS2
ORF Size: 1641 bp
RefSeq#: NM_030928
Gene Description: CDT1 is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein.
UniGene ID: Hs.122908
HGNC ID: HGNC:24576