human DGCR14 shRNA silencing AAV

Cat. No: shAAV-206913

Availability: 4-5 weeks

Name: AAV-h-DGCR14-shRNA

This is an AAV expressing shRNA for silencing of Human DGCR14.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DGCR14
Gene Name: DiGeorge syndrome critical region gene 14
Gene ID: 8220
Gene Synonyms: DGCR13; DGS-H; DGS-I; DGSH; DGSI; ES2; Es2el
ORF Size: 1431 bp
RefSeq#: NM_022719
Gene Description: DGCR14 is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders include DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and some familial or sporadic conotruncal cardiac defects which have been associated with microdeletion of 22q11.2. The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus.
UniGene ID: Hs.716675
HGNC ID: HGNC:16817