mouse CCR5 shRNA silencing AAV

Cat. No: shAAV-254905

Availability: 6-8 weeks

Name: AAV-m-CCR5-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ccr5.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ccr5
Gene Name: chemokine (C-C motif) receptor 5
Gene ID: 12774
Gene Synonyms: AM4-7; CD195; Cmkbr5
ORF Size: 1065 bp
RefSeq#: NM_009917
Gene Description: Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
UniGene ID: Mm.14302