human DYRK2 shRNA silencing AAV

Cat. No: shAAV-207482

Availability: 4-5 weeks

Name: AAV-h-DYRK2-shRNA

This is an AAV expressing shRNA for silencing of Human DYRK2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DYRK2
Gene Name: dual specificity tyrosine phosphorylation regulated kinase 2
Gene ID: 8445
ORF Size: 1806 bp
RefSeq#: NM_003583
Gene Description: DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.
UniGene ID: Hs.173135
HGNC ID: HGNC:3093