human FRAT1 shRNA silencing AAV

Cat. No: shAAV-209304

Availability: 6-8 weeks

Name: AAV-h-FRAT1-shRNA

This is an AAV expressing shRNA for silencing of Human FRAT1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FRAT1
Gene Name: FRAT1, WNT signaling pathway regulator
Gene ID: 10023
ORF Size: 840 bp
RefSeq#: NM_005479
Gene Description: FRAT1 belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.
UniGene ID: Hs.715785
HGNC ID: HGNC:3944