mouse TCFAP2B shRNA silencing AAV

Cat. No: shAAV-273928

Availability: 6-8 weeks

Name: AAV-m-TCFAP2B-shRNA

This is an AAV expressing shRNA for silencing of Mouse Tfap2b.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Tfap2b
Gene Name: transcription factor AP-2 beta
Gene ID: 21419
Gene Synonyms: AI606113; AP-2(beta); E130018K07Rik; Tcfap2b
ORF Size: 1377 bp
RefSeq#: NM_001025305
Gene Description: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
UniGene ID: Mm.137021