human KCNK10 shRNA silencing AAV

Cat. No: shAAV-212732

Availability: 6-8 weeks

Name: AAV-h-KCNK10-shRNA

This is an AAV expressing shRNA for silencing of Human KCNK10.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KCNK10
Gene Name: potassium two pore domain channel subfamily K member 10
Gene ID: 54207
Gene Synonyms: K2p10.1; PPP1R97; TREK-2; TREK2
ORF Size: 1632 bp
RefSeq#: NM_021161
Gene Description: KCNK10 belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
UniGene ID: Hs.560255
HGNC ID: HGNC:6273