mouse PNPLA2 shRNA silencing AAV

Cat. No: shAAV-280982

Availability: 4-5 weeks

Name: AAV-m-PNPLA2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pnpla2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pnpla2
Gene Name: patatin-like phospholipase domain containing 2
Gene ID: 66853
Gene Synonyms: 0610039C21Rik; 1110001C14Rik; Atgl; TTS-2.2
ORF Size: 1461 bp
RefSeq#: NM_025802
Gene Description: Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
UniGene ID: Mm.29998