human CYP2R1 shRNA silencing AAV

Cat. No: shAAV-206497

Availability: 4-5 weeks

Name: AAV-h-CYP2R1-shRNA

This is an AAV expressing shRNA for silencing of Human CYP2R1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CYP2R1
Gene Name: cytochrome P450 family 2 subfamily R member 1
Gene ID: 120227
ORF Size: 1506 bp
RefSeq#: NM_024514
Gene Description: CYP2R1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.
UniGene ID: Hs.371427
HGNC ID: HGNC:20580