human PARK7 shRNA silencing AAV

Cat. No: shAAV-218226

Availability: 4-5 weeks

Name: AAV-h-PARK7-shRNA

This is an AAV expressing shRNA for silencing of Human PARK7.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PARK7
Gene Name: Parkinsonism associated deglycase
Gene ID: 11315
Gene Synonyms: DJ-1; DJ1; HEL-S-67p
ORF Size: 570 bp
RefSeq#: NM_007262
Gene Description: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
UniGene ID: Hs.419640
HGNC ID: HGNC:16369