human DKK1 shRNA silencing AAV

Cat. No: shAAV-207023

Availability: 4-5 weeks

Name: AAV-h-DKK1-shRNA

This is an AAV expressing shRNA for silencing of Human DKK1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DKK1
Gene Name: dickkopf WNT signaling pathway inhibitor 1
Gene ID: 22943
Gene Synonyms: DKK-1; SK
ORF Size: 801 bp
RefSeq#: NM_012242
Gene Description: DKK1 encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
UniGene ID: Hs.40499
HGNC ID: HGNC:2891