human TRAPPC2 shRNA silencing AAV

Cat. No: shAAV-226350

Availability: 4-5 weeks

Name: AAV-h-TRAPPC2-shRNA

This is an AAV expressing shRNA for silencing of Human TRAPPC2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TRAPPC2
Gene Name: trafficking protein particle complex 2
Gene ID: 6399
Gene Synonyms: hYP38334; MIP2A; SEDL; SEDT; TRAPPC2P1; TRS20; ZNF547L
ORF Size: 423 bp
RefSeq#: NM_014563
Gene Description: TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.622292
HGNC ID: HGNC:23068