human BCL3 shRNA silencing AAV

Cat. No: shAAV-202054

Availability: 4-5 weeks

Name: AAV-h-BCL3-shRNA

This is an AAV expressing shRNA for silencing of Human BCL3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BCL3
Gene Name: B-cell CLL/lymphoma 3
Gene ID: 602
Gene Synonyms: BCL4; D19S37
ORF Size: 1341 bp
RefSeq#: NM_005178
Gene Description: BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
UniGene ID: Hs.31210
HGNC ID: HGNC:998