human TARBP2 shRNA silencing AAV

Cat. No: shAAV-224972

Availability: 6-8 weeks

Name: AAV-h-TARBP2-shRNA

This is an AAV expressing shRNA for silencing of Human TARBP2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TARBP2
Gene Name: TARBP2, RISC loading complex RNA binding subunit
Gene ID: 6895
Gene Synonyms: LOQS; TRBP; TRBP1; TRBP2
ORF Size: 1101 bp
RefSeq#: NM_004178
Gene Description: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
UniGene ID: Hs.326
HGNC ID: HGNC:11569