human CPN1 shRNA silencing AAV

Cat. No: shAAV-205899

Availability: 4-5 weeks

Name: AAV-h-CPN1-shRNA

This is an AAV expressing shRNA for silencing of Human CPN1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CPN1
Gene Name: carboxypeptidase N subunit 1
Gene ID: 1369
Gene Synonyms: CPN; SCPN
ORF Size: 1377 bp
RefSeq#: NM_001308
Gene Description: Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.
UniGene ID: Hs.2246
HGNC ID: HGNC:2312