human MC3R shRNA silencing AAV

Cat. No: shAAV-215135

Availability: 6-8 weeks

Name: AAV-h-MC3R-shRNA

This is an AAV expressing shRNA for silencing of Human MC3R.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MC3R
Gene Name: melanocortin 3 receptor
Gene ID: 4159
Gene Synonyms: BMIQ9; MC3; MC3-R; OB20; OQTL
ORF Size: 1083 bp
RefSeq#: NM_019888
Gene Description: MC3R encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. MC3R maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
UniGene ID: Hs.248018
HGNC ID: HGNC:6931