mouse DHRS4 shRNA silencing AAV

Cat. No: shAAV-257144

Availability: 4-5 weeks

Name: AAV-m-DHRS4-shRNA

This is an AAV expressing shRNA for silencing of Mouse Dhrs4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Dhrs4
Gene Name: dehydrogenase/reductase (SDR family) member 4
Gene ID: 28200
Gene Synonyms: AI043103; AI790593; CR; D14Ucla2; mouNRDR; NDRD; PHCR; PSCD; RRD
ORF Size: 840 bp
RefSeq#: NM_030686
Gene Description: Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity).
UniGene ID: Mm.27427