mouse GULP1 shRNA silencing AAV

Cat. No: shAAV-260956

Availability: 4-5 weeks

Name: AAV-m-GULP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Gulp1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Gulp1
Gene Name: GULP, engulfment adaptor PTB domain containing 1
Gene ID: 70676
Gene Synonyms: 3110030A04Rik; 5730529O06Rik; CED-6; Ced6; GULP; Gulp-2
ORF Size: 915 bp
RefSeq#: NM_028450
Gene Description: GULP1 may function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
UniGene ID: Mm.133132