human CACNA1G shRNA silencing AAV

Cat. No: shAAV-203903

Availability: 6-8 weeks

Name: AAV-h-CACNA1G-shRNA

This is an AAV expressing shRNA for silencing of Human CACNA1G.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CACNA1G
Gene Name: calcium voltage-gated channel subunit alpha1 G
Gene ID: 8913
Gene Synonyms: Ca(V)T.1; Cav3.1; NBR13; SCA42
ORF Size: 6786 bp
RefSeq#: NM_018896
Gene Description: Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UniGene ID: Hs.591169
HGNC ID: HGNC:1394