mouse BCL2L1 shRNA silencing AAV

Cat. No: shAAV-253886

Availability: 4-5 weeks

Name: AAV-m-BCL2L1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Bcl2l1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Bcl2l1
Gene Name: BCL2-like 1
Gene ID: 12048
Gene Synonyms: Bcl(X)L; bcl-x; Bcl-XL; bcl2-L-1; Bcl2l; BclX
ORF Size: 702 bp
RefSeq#: NM_009743
Gene Description: Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis|Function: Isoform Bcl-X(S) promotes apoptosis.
UniGene ID: Mm.238213