human ALDH1L2 shRNA silencing AAV

Cat. No: shAAV-200731

Availability: 6-8 weeks

Name: AAV-h-ALDH1L2-shRNA

This is an AAV expressing shRNA for silencing of Human ALDH1L2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ALDH1L2
Gene Name: aldehyde dehydrogenase 1 family member L2
Gene ID: 160428
Gene Synonyms: mtFDH
ORF Size: 2772 bp
RefSeq#: NM_001034173
Gene Description: ALDH1L2 encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.42572
HGNC ID: HGNC:26777