mouse HSPA1A shRNA silencing AAV

Cat. No: shAAV-277566

Availability: 6-8 weeks

Name: AAV-m-HSPA1A-shRNA

This is an AAV expressing shRNA for silencing of Mouse Hspa1a.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Hspa1a
Gene Name: heat shock protein 1A
Gene ID: 193740
Gene Synonyms: hsp68; Hsp70-3; Hsp70.3; hsp70A1; Hsp72
ORF Size: 1926 bp
RefSeq#: NM_010479
Gene Description: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
UniGene ID: Mm.6388