human MMP1 shRNA silencing AAV

Cat. No: shAAV-215567

Availability: 6-8 weeks

Name: AAV-h-MMP1-shRNA

This is an AAV expressing shRNA for silencing of Human MMP1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MMP1
Gene Name: matrix metallopeptidase 1
Gene ID: 4312
Gene Synonyms: CLG; CLGN
ORF Size: 1410 bp
RefSeq#: NM_002421
Gene Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.83169
HGNC ID: HGNC:7155