human APOA4 shRNA silencing AAV

Cat. No: shAAV-201169

Availability: 6-8 weeks

Name: AAV-h-APOA4-shRNA

This is an AAV expressing shRNA for silencing of Human APOA4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: APOA4
Gene Name: apolipoprotein A4
Gene ID: 337
ORF Size: 1191 bp
RefSeq#: NM_000482
Gene Description: Apoliprotein (apo) A-IV gene contains 3 exons separated by two introns. A sequence polymorphism has been identified in the 3'UTR of the third exon. The primary translation product is a 396-residue preprotein which after proteolytic processing is secreted its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.
UniGene ID: Hs.591940
HGNC ID: HGNC:602