human PMPCB shRNA silencing AAV

Cat. No: shAAV-233329

Availability: 6-8 weeks

Name: AAV-h-PMPCB-shRNA

This is an AAV expressing shRNA for silencing of Human PMPCB.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PMPCB
Gene Name: peptidase, mitochondrial processing beta subunit
Gene ID: 9512
Gene Synonyms: Beta-MPP; MPP11; MPPB; MPPP52; P-52
ORF Size: 1444 bp
RefSeq#: NM_004279
Gene Description: PMPCB is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.
HGNC ID: HGNC:9119