human TMEM127 shRNA silencing AAV

Cat. No: shAAV-225728

Availability: 6-8 weeks

Name: AAV-h-TMEM127-shRNA

This is an AAV expressing shRNA for silencing of Human TMEM127.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TMEM127
Gene Name: transmembrane protein 127
Gene ID: 55654
ORF Size: 717 bp
RefSeq#: NM_017849
Gene Description: TMEM127 encodes a transmembrane protein with 3 predicted transmembrane domains. The protein is associated with a subpopulation of vesicular organelles corresponding to early endosomal structures, with the Golgi, and with lysosomes, and may participate in protein trafficking between these structures. Mutations in this gene and several other genes cause pheochromocytomas. Alternatively spliced transcript variants encoding the same protein have been identified.
UniGene ID: Hs.355708
HGNC ID: HGNC:26038