human FBXO5 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-208823
Availability:
4-5 weeks
Name:
AAV-h-FBXO5-shRNA
This is an AAV expressing shRNA for silencing of Human FBXO5.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- FBXO5
- Gene Name
- F-box protein 5
- Gene ID
- 26271
- Gene Synonyms
- EMI1; FBX5; Fbxo31
- ORF Size
- 1344 bp
- RefSeq#
- NM_012177
- Gene Description
- FBXO5 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified.
- UniGene ID
- Hs.520506
- HGNC ID
- HGNC:13584
Related Products
Product | Cat No. |
---|---|
AAV-h-FBXO5 | AAV-208823 |
AAV-m-FBXO5 | AAV-259254 |
Ad-h-FBXO5 | ADV-208823 |
Ad-m-FBXO5 | ADV-259254 |
AAV-m-FBXO5-shRNA | shAAV-259254 |
Ad-h-FBXO5-shRNA | shADV-208823 |
Ad-m-FBXO5-shRNA | shADV-259254 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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