human FAM38B shRNA silencing AAV

Cat. No: shAAV-208552

Availability: 4-5 weeks

Name: AAV-h-FAM38B-shRNA

This is an AAV expressing shRNA for silencing of Human PIEZO2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PIEZO2
Gene Name: piezo type mechanosensitive ion channel component 2
Gene ID: 63895
Gene Synonyms: C18orf30; C18orf58; DA3; DA5; DAIPT; FAM38B; FAM38B2; HsT748; HsT771; MWKS
ORF Size: 1632 bp
RefSeq#: NM_022068
Gene Description: Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The PIEZO2 protein has a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons (Coste et al., 2010 (PubMed 20813920)).(supplied by OMIM, Nov 2010)
UniGene ID: Hs.585839
HGNC ID: HGNC:26270