mouse TNFSF11 shRNA silencing AAV

Cat. No: shAAV-274722

Availability: 6-8 weeks

Name: AAV-m-TNFSF11-shRNA

This is an AAV expressing shRNA for silencing of Mouse Tnfsf11.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Tnfsf11
Gene Name: tumor necrosis factor (ligand) superfamily, member 11
Gene ID: 21943
Gene Synonyms: Ly109l; ODF; OPGL; RANKL; Trance
ORF Size: 951 bp
RefSeq#: NM_011613
Gene Description: Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
UniGene ID: Mm.249221