mouse CUEDC2 shRNA silencing AAV

Cat. No: shAAV-256367

Availability: 4-5 weeks

Name: AAV-m-CUEDC2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cuedc2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cuedc2
Gene Name: CUE domain containing 2
Gene ID: 67116
Gene Synonyms: 3010002G01Rik
ORF Size: 855 bp
RefSeq#: NM_024192
Gene Description: Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
UniGene ID: Mm.218848