human ITGA6 shRNA silencing AAV

Cat. No: shAAV-212483

Availability: 4-5 weeks

Name: AAV-h-ITGA6-shRNA

This is an AAV expressing shRNA for silencing of Human ITGA6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ITGA6
Gene Name: integrin subunit alpha 6
Gene ID: 3655
Gene Synonyms: CD49f; ITGA6B; VLA-6
ORF Size: 3222 bp
RefSeq#: NM_000210
Gene Description: The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.133397
HGNC ID: HGNC:6142